ddX is an open-source software package for continuum solvation models based on the domain decomposition paradigm. It contains a common interface for the three different methods ddCOSMO, ddPCM and ddLPB for the numerical solution to the COSMO, PCM and LPB solvation models. ddX computes for these methods the electrostatic contribution to the solvation energy, the corresponding contribution to the forces and/or the contribution to the Fock- or DFT Kohn-Sham-matrix. Using a common Python interface, all three methods are accessible from a host-code that is used to model the solute. The host code can be on the level of QM, QM/MM, polarizable MM or MM. In this fashion an interface to Psi4 has been recently realised. Additionally a standalone application, the *ddx_driver* is available.

For referencing the library and methods, see the list of relevant references.